Development of a buccal mucoadhesive film for fast dissolution: mathematical rationale, production and physicochemical characterization
نویسندگان
چکیده
منابع مشابه
preparation and physicochemical evaluation of nystatine mucoadhesive buccal film
abstract: background: a new type of drug delivery system known as mucoadhesive film has been developed for oral thrush treatment. due to comfortable use of this drug delivery system, this would be encouragingly utilized, especially in babies and patient under chemotherapy. nystatin mucoadhesive film (nmf) is a polymeric film which is adhered to front upper gum and back to the upper lip and rele...
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Background: Recently, the mucosa has attracted attention due to its large arteries and high permeability for drug delivery. Due to the anti-inflammatory effect of parsley and easy access to this plant in Iran and the fact that the adhesive mucosa film is a new method with high performance and efficiency of drug transfer, this study was done to evaluate the effect of this plant on the pharyngiti...
متن کاملOral Mucoadhesive Buccal Film of Ciprofloxacin for Periodontitis: Preparation and Characterization
Purpose: To prepare and characterise ciprofloxacin mucoadhesive buccal films for localised, improved drug delivery in periodontitis. Methods: Ciprofloxacin-loaded buccal films containing 50 mg ciprofloxacin were prepared mucoadhesive polymers sodium cellulose (SCMC) and sodium alginate, using a solvent evaporation method. The films were evaluated in terms of thickness, weight, folding endurance...
متن کاملDevelopment of Mucoadhesive Buccal Films of Glipizide
For improving bioavailability in controlled release fashion and to circumvent the hepatic first pass effect of glipizide mucoadhesive buccal films of glipizide were prepared by solvent casting technique. Buccal films were prepared using hydroxy propylmethylcellulose, sodium carboxymethylcellulose, carbopol934P and Eudragit RL-100. Films were evaluated for their weight, thickness, surface pH, sw...
متن کاملDevelopment and characterization of mucoadhesive patches of salbutamol sulfate for unidirectional buccal drug delivery.
Buccal patches of salbutamol sulfate were prepared using five different water soluble polymers in various proportions and combinations using PEG-400/PG as plasticizers. A 32 full factorial design was used to design the experiments for each polymer combination. Patches were laminated on one side with a water impermeable backing layer for unidirectional drug release. The thickness of medicated pa...
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ژورنال
عنوان ژورنال: Drug Delivery
سال: 2013
ISSN: 1071-7544,1521-0464
DOI: 10.3109/10717544.2013.851301